![]() ![]() Progesterone production is the domain of the ovary until the placenta takes over progesterone production at around 8-10 weeks gestational age. *SIDENOTE: some clinics have moved to modified natural cycle FET preps in which the luteal phase is supported by the body’s own progesterone AND supplemented with exogenous progesterone as well. More clinics might prefer progesterone injections in FET cycles. As a result, FET cycles are completely reliant on progesterone as a REPLACEMENT.* There are fewer studies and less agreement about the equivalence of progesterone injections and progesterone vaginal suppositories in FET cycles. Unlike in a fresh IVF cycle where your body makes some progesterone, in * most* frozen embryo transfer (FET) cycles, your body does not make any progesterone. Eitherway, if you are not tolerating injections, talk to your doctor about whether vaginal progesterone is right for you. Interestingly, some patients prefer injections over vaginal suppositories. Studies have shown that progesterone injections are equivalent to vaginal progesterone suppositories in FRESH IVF cycles as it relates to livebirth rates. Which route and for how long, though, have been questions studied for some time and practice patterns vary by clinic so talk to your MD about what is right for you. As a result, progesterone supplementation is required in IVF. When one undergoes a fresh IVF cycle for example, all of those follicles that are aspirated at the time of egg retrieval makde progesterone but the hormone signals from the brain that KEEP those follicles making progesterone is blunted by the IVF medications that are responsible for prevented ovulation. Progesterone helps support implantation and the IVF process blunts your body’s natural ability to make progesterone. Patients that no longer wish to store their frozen embryos have several options, which we can discuss with you if that time should arise.Progesterone and IVF: So why do I need this? What are the options if I no longer want to keep frozen embryos in storage? It is the patient’s responsibility to notify us of any change in address. The charge for embryo freezing includes the cost of storage for one year. Most likely they can be stored indefinitely.Ī careful inventory is kept for all embryos in storage by our laboratory. It is not known how long embryos can be safely frozen, although there have been successful pregnancies even after being frozen for 10 years. How Long Can My Embryos Be Stored?Įmbryo freezing has been performed since the 1980’s. Previously-frozen embryos have a greater than 95% survival rate and pregnancy rates from frozen embryos are excellent. There is no data that any one protocol works better than another and the protocol chosen is based upon your specific needs. Both use hormones, including estrogen and progesterone, to prepare the uterus for embryo implantation. Embryo transfer is usually done on either the 4th or 6th day of progesterone, depending on which day following fertilization the embryo had been frozen. There are two protocols used for FET cycles. Next, the patient will be prescribed medications to increase uterine lining thickness, preparing it for implantation. Before starting an FET cycle, the physician will assess the patient’s hormone status and the uterus to ensure there are no abnormalities that have developed since the first IVF cycle. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |